• As described in the introductory section

  2024-09-29

  

  As described in the introductory section, the rotifer nervous system would be capable to transmit high-affinity rnase inhibitor for RNA protection in throughout its neural pathways. In addition, Clément and Amsellem (1989) and Kotikova et al. (2001) suggested acetylcholine to be important for the f

• br Conflict of interest br Acknowledgments This work was

  2024-09-29

  

  Conflict of interest Acknowledgments This work was supported by research grant [PR26/20326] from Santander Bank/UCM. The authors would like to thank Miguel Capo, Professor of Toxicology from the Universidad Complutense de Madrid, for his counseling during the preparation of the present work.

• br Discussion In our current study we demonstrated that

  2024-09-29

  

  Discussion In our current study, we demonstrated that both the metastatic and recurrent ovarian cancer tissues expressed lower levels of p62 when compared with the patient-matched primary tumor samples. High Spadin receptor levels of p62 were associated with long progression-free survival of pati

• Maintaining the normal vaginal fluid

  2024-09-28

  

  Maintaining the normal vaginal fluid acidity is important for vaginal functions (Wagner and Levin 1984). Estrogen has been shown essential in maintaining the acidity of vaginal fluid, in which its deficiency could cause vaginal fluid pH to increase (Gorodeski et al. 2005). After menopause, low estro

• In the last decade the zebrafish has emerged

  2024-09-28

  

  In the last decade, the zebrafish has emerged as a valuable vertebrate model to systematically dissect the genetic underpinnings of both vertebrate heart development and function [8,9], as well as distinct cardiac diseases such as congenital heart disease [10], cardiomyopathies [11,12] and cardiac a

• Although the LB domains of mGlu receptors have not

  2024-09-28

  

  Although the LB2 domains of mGlu receptors have not been shown to form an extensive interface during activation, they do draw closer to each other, as demonstrated in crystal structures (Kunishima et al., 2000, Muto et al., 2007, Tsuchiya et al., 2002) and by FRET analysis (Doumazane et al., 2013, V

• br Extracellular domain architecture The extracellular regio

  2024-09-28

  

  Extracellular domain architecture The extracellular region of GABAB receptor exists in a heterodimeric configuration regardless of interactions within the rest of the protein (Geng et al., 2012, Liu et al., 2004, Nomura et al., 2008). The extracellular domains of the GABAB1 and GABAB2 subunits ar

• br Materials and methods br Results br Discussion

  2024-09-28

  

  Materials and methods Results Discussion In the present study, we found that SSTR2, SSTR5, and DA2R proteins are expressed in ACTH-positive fak pathway in healthy canine pituitary glands, with particularly high positive cell ratios in the intermediate lobes. Somatostatin has been reported t

• br Materials and methods br Results br

  2024-09-28

  

  Materials and methods Results Discussion Fluoride can readily penetrate cellular membranes and seriously damage the structure and physiological function of cells (Zhou et al., 2015). Several studies have shown that excessive fluoride can decrease the viability of cells and that the growth o

• In another study Yerra and Kumar

  2024-09-28

  

  In another study, Yerra and Kumar (2016) used streptozotocin to induce diabetic neuropathy in rats. Mechanical/thermal hyperalgesia, motor/sensory nerve conduction velocities (MNCV and SNCV) and sciatic nerve blood flow (NBF) were evaluated. In vitro studies of Neuro2a (N2A) cell culture were perfor

• Aldose reductase ALR EC the first enzyme in the polyol

  2024-09-28

  

  Aldose reductase (ALR2, EC1.1.1.21), the first enzyme in the polyol pathway, is a monomeric oxidoreductase that catalyses the NADPH-dependent reduction of a wide variety of carbonyl compounds, especially glucose. In this metabolism pathway, glucose is firstly reduced to sorbitol catalyzed by ALR2 wi

• Di ethylhexyl phthalate DEHP is one of

  2024-09-28

  

  Di-(2-ethylhexyl) phthalate (DEHP) is one of the most widely used environmental chemicals in the production of polyvinyl chloride. After wh4 into human body, DEHP can be converted to the metabolite mono-ethylhexyl phthalate (MEHP), which has higher toxicity than DEHP and can influence reproductive

• Anti LT therapy by LO inhibition has been

  2024-09-27

  

  Anti-LT therapy by 5-LO inhibition has been hampered by occurring liver toxicities by Zileuton or the clinical phase II compound Atreleuton [36], [37] However both compounds possess a thiophene as well as an N-hydroxyurea moiety. These features could be linked with reactive thiophene intermediates [

• Optimizing TSA amplification for high sensitivity The combin

  2024-09-27

  

  The combination of Aurora kinase inhibitors with standard chemotherapeutics or radiotherapeutics are currently in progress, such as AZD1152 plus radiotherapy in various solid cancer models. In addition, Azzariti et al. found that AZD1152-HQPA enhanced oxaliplatin and gemcitabine effectiveness in the

• br Acknowledgments br Introduction Human innate immune syste

  2024-09-27

  

  Acknowledgments Introduction Human innate immune system provides first line of defense against multiple viral or bacterial attacks, and provides critical surveillance against oncogenic development. Evidences show that individuals with primary immunodeficiency or induced immunosuppression durin

14241 records 46/950 page Previous Next First page 上5页 4647484950 下5页 Last page